Synchrotron based X-ray and IR spectro-microscopy on the cellular level
Vendredi 31 mai 2013 15:30
- Duree : 1 heure
Lieu : Room 500 - 501, Central Building, ESRF - 6 Rue Jules Horowitz - Grenoble
Orateur : Tanja DUCIC
Significant progress has been made in the field of X-ray microscopy, through developments X-ray tools i.e. source, optics and imaging methodologies, as well as through a wide range of applications in bio-imaging during last years. The high penetration of X-rays combined with high spatial resolution, make X-ray microscopy ideal tool for 2- and 3-D for structural visualization on subcellular level. X-ray fluorescence is particularly suited for quantifying trace elements in single cells in situ ; exploiting on an inherent property of matter, elemental contrast is not reliant on artificial dyes or fluorophores. On the other hand FTIR imaging technique is based on the contrast of the local density of vibrational states characteristic for functional molecular groups, and the synchrotron radiation is the most useful source for IR. Both techniques are very important tools for imaging of the cellular compounds, without any staining, labelling or cutting artefacts. Correlative imaging, or combination of different imaging techniques e.g. X-ray and IR, is also significantly developing in recent times. This presentation will cover up-to-date my work in the application of X-ray and FTIR spectro-microscopy techniques in the bio-medical science, especially neural-imaging.
Contact : marine.cotte@esrf.fr
Discipline évènement : (Physique)
Entité organisatrice : (ESRF)
Nature évènement : (Séminaire)
Evènement répétitif : (Séminaire ESRF)
Site de l'évènement : Polygone scientifique
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