Neutrons describe ectoine effects on water H-bonding and hydration around a soluble protein and a cell membrane
Mardi 27 septembre 2016 11:00
- Duree : 1 heure
Lieu : ILL 4, Amphi Chadwick - 71 avenue des Martyrs - Grenoble
Orateur : Giuseppe ZACCAI (Institut Laue-Langevin)
Understanding microbe adaptation to extreme environments remains a challenge of high biotechnological potential in important areas such as healthcare, bioremediation and waste management. It has been estimated, for example, that a rust-producing Halomonas species could bring about the total deterioration of the sunken RMS Titanic by 2030.
Halomonas microorganisms isolated from the oceans or salt marshes, reversibly accumulate high concentrations of the molecule ectoine, within their cells, to counterbalance fluctuating external salt concentrations.
Neutron scattering experiments on D4, D16, D22 and IN12 were designed in order to understand how ectoine permits Halomonas to survive in their extreme environment. They revealed that within the microbe cells, ectoine acts by stabilising the hydration layer around proteins and membranes and by enhancing the remarkable dynamic properties of water that are essential to life processes.
Contact : dubouloz@ill.fr
Discipline évènement : (Physique)
Entité organisatrice : (ILL)
Nature évènement : (Séminaire)
Evènement répétitif : (General ILL Seminar - College 6)
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Evènement répétitif : (General ILL Seminar - College 7)
Site de l'évènement : Polygone scientifique
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