An apple a day ....

Orateur : Martin TOLLINGER (Institute of Organic Chemistry, Innsbruck University, Austria)

Allergies against birch pollen are caused by different isoforms of the protein Bet v 1, affecting up to 25 percent of the population in Central and Northern Europe. While crystal structures of various Bet v 1 isoforms have been known for more than a decade, the observed drastic immunologic differences between them have remained unclear. I will present recent solution NMR data that provide insight into the interplay between structural flexibility and allergic potential. Additional data regarding cross-reactive food allergens from apples and how these relate to birch pollen allergies will be dicussed.

Télécharger dans mon agenda