Amyloid, amyloidosis and therapeutic progress

Orateur : Sir Mark PEPYS (Director, Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Royal Free Campus, University College London)

Words and names are important in science and medicine. Amyloid and amyloidosis provide an instructive paradigm of this eternal truth. Although the definition of these terms is simple, straightforward and unequivocal, they are widely and grossly misused, to the detriment of understanding and, crucially, potentially also to progress in treatment for major unmet medical needs. These issues will be defined and discussed in relation to the very exciting and encouraging recent progress in development and testing of novel therapeutic approaches to systemic amyloidosis and Alzheimer’s disease.

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