BUILDING ON BIOMIMETICS : BIOINSPIRATION AND NANOTECHNOLOGIES FOR DEVELOPING MEDICAL DEVICES ?
Vendredi 26 octobre 2018 12:30
- Duree : 45 minutes
Lieu : Amphithéâtre MINATEC - 3 parvis Louis Néel - 38000 Grenoble
Orateur : Donald MARTIN (Université Grenoble Alpes - Laboratoire TIMC-IMAG)
The development of novel medical devices is based increasingly on the use of nanotechnologies. This approach seems to be driven by the concept of “bioinspiration”, which is usually interpreted as providing biological-like characteristics for synthetic materials and processes. In this presentation I will discuss a variation on that theme of bioinspiration by considering how biological components could improve the design and function of medical devices. I will use examples of such devices from my team, including the first implantable enzymatic glucose biofuel cell [PLoS ONE, 5(5):e10476, 2010], which was optimised by using modified biopolymers [Chem.Comms, 50:14535, 2014] to enhance bioelectrode catalytic activity when implanted for long periods [Energy.Env.Sci, 8:1017, 2015] that has now led to implantation of a functional, wirelessly controlled autonomous device [Electrochem. Acta, 269:360, 2018]. The theme of bioinspiration by utilising biological components is also exemplified from our development and optimisation of biomimetic membrane systems, which can be used for biomimetic biofuel cells that generate electricity by imitating biological salt transport [Adv.Func.Mater, 19:201, 2009] or potentially for novel biosensors [Sci. Rep, 7:3399, 2017]. The ongoing improvements in stability and performance of such medical devices will need further bioinspired approaches to develop these to be symbiotic biocompatible systems.
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