Functional genomics at/near the single cell resolution

Orateur : Ljiljana PASA-TOLIC (Pacific Northwest National Laboratory (PNNL), USA)

Dr. Ljiljana Paša-Tolić is a Laboratory Fellow at Pacific Northwest National Laboratory (PNNL) and Deputy for Technology at the Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility operated by PNNL for the U.S. Department of Energy. Her research centers on developing sophisticated analytical methods with emphasis on advanced mass spectrometry and micro-separations, as well as the application of these techniques for the accurate determination of spatiotemporal changes in protein and metabolites. She published over 200 peer-reviewed journal articles, building an international expertise in developing proteomic strategies for identification and quantitation of proteins in intact state, creating breakthrough instrumentation and novel strategies for proteomics and metabolomics. Most recently, she led the development of EMSL’s 21 Tesla Fourier transform ion cyclotron resonance mass spectrometer, and established MS imaging capabilities comprised of SIMS, MALDI- and several ambient ionization (e.g., Laser Ablation ESI, LAESI) platforms, for applications ranging from environmental ecology to medicine and molecular histology.

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