CHARM OF DENDRIMER NANOTECHNOLOGY FOR BIOMEDICAL APPLICATIONS
Mardi 29 octobre 2019 11:00
- Duree : 1 heure
Lieu : Salle de Conférence de l’IAB - Rond Point de La Chantourne, 38700 La Tronche (arrêt de tram Grand Sablon, ligne B)
Orateur : Ling PENG (CINAM, Marseille)
The application of nanotechnology to engineer nanovectors for drug delivery is widely expected to bring breakthrough and create entirely novel therapeutics. Dendrimers are ideal nanocarriers for drug delivery by virtue of their uniquely well-defined structure and multivalent cooperativity.1 We have recently established bio-inspired structurally flexible dendrimers2 and self-assembled supramolecular dendrimers3 for drug delivery. In particular, self-assembling dendrimers are able to
form modular, adaptive and responsive nanosystems, and effectively deliver various chemo- and bio-therapeutics as well as imaging agents3 for diagnosis, cancer therapy, gene therapy and immunotherapy, offering new perspectives in nanotechnology based biomedical applications for personalized medicine.
1. Lyu & Peng , Nat. Biomed. Eng. 2017, 1, 686 ; Lyu et al, Mater Today Chem. 2019, 13, 34.
2. Cui et al, Nat. Commun. 2016, 7, 10637 ; Ma et al, Mol. Ther., 2018, 26, 70.
3. Wei et al, Proc. Natl. Acad. Sci. U.S.A. 2015, 112, 2978 ; Dong et al, J. Am. Chem. Soc. 2018,140,16264 ; Garrigue et al, Proc. Natl. Acad. Sci. U.S.A. 2018, 115,11454 ; Ellert-Miklaszewsk
et al, Nanomedicine, 2019, Doi : 10.2217/nnm-2019-0176
Contact : karin.sadoul@univ-grenoble-alpes.fr
Discipline évènement : (Biologie / Chimie)
Entité organisatrice : (IAB)
Nature évènement : (Séminaire)
Evènement répétitif : (Mardis de l’IAB)
Site de l'évènement : Pôle Santé / La Tronche
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